pvrl4 protein  (Human Protein Atlas)

Journal: Molecular Oncology

Article Title: MiR‐31 and miR‐128 regulates poliovirus receptor‐related 4 mediated measles virus infectivity in tumors

doi: 10.1016/j.molonc.2016.07.007

Figure Lengend Snippet: PVRL4 protein levels are increased with unchanged PVRL4 mRNA levels in malignant tumors. Representative western blots and quantification of blots in glioblastoma (A and B) (n = 18), breast cancer (D and E) (n = 15) and ...

Article Snippet: Reymond et al. (2001) and the Human Protein Atlas Project ( www.proteinatlas.org ) have shown that PVRL4 is expressed not only in the placental trophoblasts, brain, lung, testis glandular cells of the stomach, but also adenocarcinomas of the lung, breast, ovary and glioblastoma.

Techniques: Western Blot

Journal: Molecular Oncology

Article Title: MiR‐31 and miR‐128 regulates poliovirus receptor‐related 4 mediated measles virus infectivity in tumors

doi: 10.1016/j.molonc.2016.07.007

Figure Lengend Snippet: Increased PVRL4 IHC staining in malignant tumors. Gliosis (control) (A–D) glioblastoma (E–F), normal breast (G), breast tumor (H), benign ovarian (K) and malignant ovarian tumor (L) samples stained with PVRL4 antibody (X20). Representation ...

Article Snippet: Reymond et al. (2001) and the Human Protein Atlas Project ( www.proteinatlas.org ) have shown that PVRL4 is expressed not only in the placental trophoblasts, brain, lung, testis glandular cells of the stomach, but also adenocarcinomas of the lung, breast, ovary and glioblastoma.

Techniques: Immunohistochemistry, Control, Staining

Journal: Molecular Oncology

Article Title: MiR‐31 and miR‐128 regulates poliovirus receptor‐related 4 mediated measles virus infectivity in tumors

doi: 10.1016/j.molonc.2016.07.007

Figure Lengend Snippet: MiR‐31 and miR‐128 regulates PVRL4. Human PVRL4 3′UTR firefly luciferase (wild‐type or mutant (see Figure 3B)) and Renilla luciferase plasmid constructs were transfected (0.8 μg in 96 well plates) ...

Article Snippet: Reymond et al. (2001) and the Human Protein Atlas Project ( www.proteinatlas.org ) have shown that PVRL4 is expressed not only in the placental trophoblasts, brain, lung, testis glandular cells of the stomach, but also adenocarcinomas of the lung, breast, ovary and glioblastoma.

Techniques: Luciferase, Mutagenesis, Plasmid Preparation, Construct, Transfection

Journal: Molecular Oncology

Article Title: MiR‐31 and miR‐128 regulates poliovirus receptor‐related 4 mediated measles virus infectivity in tumors

doi: 10.1016/j.molonc.2016.07.007

Figure Lengend Snippet: MiR‐31 and miR‐128 expressions correlate with PVRL4 levels. QRT‐PCR quantification of miR‐31(A) and miR‐128 (B) expression levels in gliosis (n = 11) and glioblastoma (n = 18) tissues. ...

Article Snippet: Reymond et al. (2001) and the Human Protein Atlas Project ( www.proteinatlas.org ) have shown that PVRL4 is expressed not only in the placental trophoblasts, brain, lung, testis glandular cells of the stomach, but also adenocarcinomas of the lung, breast, ovary and glioblastoma.

Techniques: Quantitative RT-PCR, Expressing

Journal: Molecular Oncology

Article Title: MiR‐31 and miR‐128 regulates poliovirus receptor‐related 4 mediated measles virus infectivity in tumors

doi: 10.1016/j.molonc.2016.07.007

Figure Lengend Snippet: MiR‐31 and miR‐128 modulates MV infectivity. Western blot analysis and blot quantification of PVRL4 and MV N‐protein levels following transduction with lentiviral‐vectors (MOI = 1) expressing miRNA and ...

Article Snippet: Reymond et al. (2001) and the Human Protein Atlas Project ( www.proteinatlas.org ) have shown that PVRL4 is expressed not only in the placental trophoblasts, brain, lung, testis glandular cells of the stomach, but also adenocarcinomas of the lung, breast, ovary and glioblastoma.

Techniques: Infection, Western Blot, Transduction, Expressing

Journal: Molecular Oncology

Article Title: MiR‐31 and miR‐128 regulates poliovirus receptor‐related 4 mediated measles virus infectivity in tumors

doi: 10.1016/j.molonc.2016.07.007

Figure Lengend Snippet: Anti‐miR‐31/‐128 increases MV infectivity and reduces tumor size while miR‐31 regulates MV mediated PVRL4 decrease. Tumor size differences post subcutaneous intratumoral MV administration in U87 (A), MCF7 (B) and A2780 ...

Article Snippet: Reymond et al. (2001) and the Human Protein Atlas Project ( www.proteinatlas.org ) have shown that PVRL4 is expressed not only in the placental trophoblasts, brain, lung, testis glandular cells of the stomach, but also adenocarcinomas of the lung, breast, ovary and glioblastoma.

Techniques: Infection